We report the sequential changes of retinal vessels observed by optical coherence tomography angiography (OCTA) in a case of\nnonischemic central retinal vein occlusion (CRVO) that converted to ischemic CRVO. An 81-year-old woman visited our Retina\nClinic because of visual acuity loss in the left eye. Funduscopic examination showed venous tortuosity and intraretinal hemorrhage\nin all four quadrants of the fundus. OCT showed macular edema. Fluorescein angiography (FA) and OCTA showed loss of small\ncapillaries. Nonischemic CRVO was diagnosed. Antivascular endothelial growth factor (VEGF) treatment resolved the edema and\nimproved visual acuity.However, during follow-up, capillary dropout was observed onOCTA,which gradually enlarged. Eventually,\nFAconfirmed the conversion to ischemic CRVO. In this case, sequential observations usingOCTAshowed that nonischemic CRVO\ndid not convert to ischemic CRVOabruptly but occurred stepwise.Additionally, vascular changes began around the veins and blood\nflow changes were observed more clearly in deep capillary plexus than in superficial capillary plexus.
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